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1

Selective cross-polarization in solution state NMR

CHIARPARIN, ELISABETTA, PELUPESSY, PHILIPPE, BODENHAUSEN, GEOFFREY

Journal:

Molecular Physics

Year:

1998

Language:

english

File:

PDF, 324 KB

english, 1998

2

Reducing the lipophilicity of perfluoroalkyl groups by CF2–F/CF2-Me or CF3/CH3 exchange

Jeffries, Benjamin, Wang, Zhong, Graton, Jerome, Holland, Simon David, Brind, Thomasin, Greenwood, Ryan David Robert, Le Questel, Jean-Yves, Scott, James S., Chiarparin, Elisabetta, Linclau, Bruno

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.58 MB

english, 2018

3

Hartmann–Hahn polarization transfer in liquids: An ideal tool for selective experiments

Philippe Pelupessy, Elisabetta Chiarparin

Journal:

Concepts in Magnetic Resonance Part A

Year:

2000

Language:

english

File:

PDF, 699 KB

english, 2000

4

Cover Picture

Elisabetta Chiarparin, Simon Rüdisser, Geoffrey Bodenhausen

Journal:

Year:

2001

Language:

english

File:

PDF, 23 KB

english, 2001

5

Hydrogen Bonds in RNA Base Pairs Investigated by Cross-Correlated Relaxation of Multiple-Quantum Coherence in NMR

Elisabetta Chiarparin, Simon Rüdisser, Geoffrey Bodenhausen

Journal:

Year:

2001

Language:

english

File:

PDF, 243 KB

english, 2001

6

Cyclische Metallkomplexe mit Nucleobasen und anderen Heterocyclen: molekulare Schachteln, Rechtecke und Sechsecke

Dr. Holger Rauter, Colin J. L. Lock, Dr. Pilar Amo-Ochoa, Dipl.-Chem. Eva Freisinger, Prof. Dr. Bernhard Lippert, Prof. Dr. Lucio Randaccio, Dr. Ennio Zangrando, Dr. Elisabetta Chiarparin, Dr. Ilpo Mu

Journal:

Angewandte Chemie

Year:

1997

Language:

german

File:

PDF, 611 KB

german, 1997

7

Cyclic Metal Complexes of Nucleobases and Other Heterocycles: Molecular Boxes, Rectangles, and Hexagons

Dr. Ilpo Mutikainen, Colin J. L. Lock, Prof. Dr. Lucio Randaccio, Dr. Ennio Zangrando, Dr. Elisabetta Chiarparin, Prof. Dr. Bernhard Lippert, Dr. Holger Rauter, Dr. Pilar Amo-Ochoa, Dipl.-Chem. Eva Fr

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 797 KB

english, 1997

8

Temperature dependence of internucleotide nitrogen–nitrogen scalar couplings in RNA

Dimitri Bytchenkoff, Elisabetta Chiarparin, Dominique Früh, Simon Rüdisser, Geoffrey Bodenhausen

Journal:

Magnetic Resonance in Chemistry

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

9

Excitation of Selected Proton Signals in NMR of Isotopically Labeled Macromolecules

Philippe Pelupessy, Elisabetta Chiarparin, Geoffrey Bodenhausen

Journal:

Journal of Magnetic Resonance

Year:

1999

Language:

english

File:

PDF, 65 KB

english, 1999

10

Measurement of Relaxation Rates of NH and Hα Backbone Protons in Proteins with Tailored Initial Conditions

Oscar Millet, Elisabetta Chiarparin, Philippe Pelupessy, Miquel Pons, Geoffrey Bodenhausen

Journal:

Journal of Magnetic Resonance

Year:

1999

Language:

english

File:

PDF, 86 KB

english, 1999

11

Qualitative EH-FMO interpretation of the 195Pt NMR shifts in heterobimetallic complexes containing the PtPdY core: an inverse halogen dependence

Fabio Pichierri, Elisabetta Chiarparin, Ennio Zangrando, Lucio Randaccio, Dagmar Holthenrich, Bernhard Lippert

Journal:

Inorganica Chimica Acta

Year:

1997

Language:

english

File:

PDF, 637 KB

english, 1997

12

Normalized one-dimensional NOE measurements in isotopically labeled macromolecules using two-way cross-polarization

Elisabetta Chiarparin, Philippe Pelupessy, Brian Cutting, Thomas R. Eykyn, Geoffrey Bodenhausen

Journal:

Journal of Biomolecular NMR

Year:

1999

Language:

english

File:

PDF, 78 KB

english, 1999

13

Simultaneous determination of Ψ and Φ angles in proteins from measurements of cross-correlated relaxation effects

Philippe Pelupessy, Elisabetta Chiarparin, Ranajeet Ghose, Geoffrey Bodenhausen

Journal:

Journal of Biomolecular NMR

Year:

1999

Language:

english

File:

PDF, 92 KB

english, 1999

14

Efficient determination of angles subtended by Cα-Hα and N-HN vectors in proteins via dipole-dipole cross-correlation§

Philippe Pelupessy, Elisabetta Chiarparin, Ranajeet Ghose, Geoffrey Bodenhausen

Journal:

Journal of Biomolecular NMR

Year:

1999

Language:

english

File:

PDF, 127 KB

english, 1999

15

In vitro measurement of drug efficiency index to aid early lead optimization

Klara Valko, Elisabetta Chiarparin, Shenaz Nunhuck, Dino Montanari

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 519 KB

english, 2012

16

Fragment-Based Discovery of 6-Azaindazoles As Inhibitors of Bacterial DNA Ligase

Howard, Steven, Amin, Nader, Benowitz, Andrew B., Chiarparin, Elisabetta, Cui, Haifeng, Deng, Xiaodong, Heightman, Tom D., Holmes, David J., Hopkins, Anna, Huang, Jianzhong, Jin, Qi, Kreatsoulas, Cons

Journal:

ACS Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.67 MB

english, 2013

17

Exploring Weak Ligand-Protein Interactions by Long-Lived NMR States: Improved Contrast in Fragment-Based Drug Screening

Buratto, Roberto, Mammoli, Daniele, Chiarparin, Elisabetta, Williams, Glyn, Bodenhausen, Geoffrey

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 745 KB

english, 2014

18

Relaxation of Two-Spin Coherence Due to Cross-Correlated Fluctuations of Dipole−Dipole Couplings and Anisotropic Shifts in NMR of 15 N, 13 C-Labeled Biomolecules

Chiarparin, Elisabetta, Pelupessy, Philippe, Ghose, Ranajeet, Bodenhausen, Geoffrey

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 130 KB

english, 1999

19

Measurement of Long-Range Cross-Correlation Rates Using a Combination of Single- and Multiple-Quantum NMR Spectroscopy in One Experiment

Früh, Dominique, Chiarparin, Elisabetta, Pelupessy, Philippe, Bodenhausen, Geoffrey

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

20

Resolving Contradictions between Overdetermined NMR Cross-Correlation Rates

Tolman, Joel R., Chiarparin, Elisabetta, Bodenhausen, Geoffrey

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 43 KB

english, 2000

21

Relative Orientation of C α H α -Bond Vectors of Successive Residues in Proteins through Cross-Correlated Relaxation in NMR

Chiarparin, Elisabetta, Pelupessy, Philippe, Ghose, Ranajeet, Bodenhausen, Geoffrey

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

22

Cytosine nucleobase as a tridentate ligand: Metal binding to N3, N4 and O2 in the trinuclear complex cis-[Pt(NH3)2(mcyt)2{Pd(en)}2][NO3]4·H2O (mcyt = 1-methylcytosinate, en = ethane-1,2-diamine)

Holthenrich, Dagmar, Zangrando, Ennio, Chiarparin, Elisabetta, Lippert, Bernhard, Randaccio, Lucio

Journal:

Journal of the Chemical Society Dalton Transactions

Year:

1997

Language:

english

File:

PDF, 121 KB

english, 1997

23

Bis(chelated) palladium(II) complexes with a diphosphine and a dinitrogen ligand: very efficient catalyst precursors in the co- and ter-polymerisation of CO and olefins

Milani, Barbara, Vicentini, Lidia, Sommazzi, Anna, Garbassi, Fabio, Chiarparin, Elisabetta, Zangrando, Ennio, Mestroni, Giovanni

Journal:

Journal of the Chemical Society Dalton Transactions

Year:

1996

Language:

english

File:

PDF, 843 KB

english, 1996

24

Application of drug efficiency index in drug discovery: a strategy towards low therapeutic dose

Montanari, Dino, Chiarparin, Elisabetta, Gleeson, Matthew Paul, Braggio, Simone, Longhi, Raffaele, Valko, Klara, Rossi, Tino

Journal:

Expert Opinion on Drug Discovery

Year:

2011

Language:

english

File:

PDF, 582 KB

english, 2011

25

Untersuchung schwacher Protein-Ligand-Wechselwirkungen mithilfe langlebiger NMR-Zustände: verbesserter Kontrast für das fragmentbasierte Wirkstoffscreening

Buratto, Roberto, Mammoli, Daniele, Chiarparin, Elisabetta, Williams, Glyn, Bodenhausen, Geoffrey

Journal:

Angewandte Chemie

Year:

2014

Language:

german

File:

PDF, 568 KB

german, 2014

26

1H,15N and13C backbone assignments of GDP-bound human H-Ras mutant G12V

Amin, Nader, Chiarparin, Elisabetta, Coyle, Joe, Nietlispach, Daniel, Williams, Glyn

Journal:

Biomolecular NMR Assignments

Year:

2016

Language:

english

File:

PDF, 491 KB

english, 2016

27

NMR backbone resonance assignment and solution secondary structure determination of human NSD1 and NSD2

Amin, Nader, Nietlispach, Daniel, Qamar, Seema, Coyle, Joe, Chiarparin, Elisabetta, Williams, Glyn

Journal:

Biomolecular NMR Assignments

Year:

2016

Language:

english

File:

PDF, 987 KB

english, 2016

28

Structure of the Epigenetic Oncogene MMSET & Inhibition by N-Alkyl Sinefungin Derivatives

Tisi, Dominic, Chiarparin, Elisabetta, Tamanini, Emiliano, Pathuri, Puja, Coyle, Joseph E., Hold, Adam, Holding, Finn P., Martin, Agnes C. L., Rich, Sharna J., Berdini, Valerio, Yon, Jeff, Acklam, Pau

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 2.42 MB

english, 2016

29

Discovery of a Potent Non-peptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-linked Inhibitor of Apoptosis Protein (XIAP)

Tamanini, Emiliano, Buck, Ildiko Maria, Chessari, Gianni, Chiarparin, Elisabetta, Day, James E. H., Frederickson, Martyn, Griffiths-Jones, Charlotte M., Hearn, Keisha, Heightman, Tom D., Iqbal, Aman,

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.60 MB

english, 2017

30

A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H ,2 H ,3 H -pyrrolo[3,2- b ]pyridin-1-yl)-2-[(2 R ,5 R )-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660)

Johnson, Christopher N., Ahn, Jong Sook, Buck, Ildiko M., Chiarparin, Elisabetta, Day, James E. H., Hopkins, Anna, Howard, Steven, Lewis, Edward J., Martins, Vanessa, Millemaggi, Alessia, Munck, Joann

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 5.35 MB

english, 2018

31

Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6

McCoull, William, Cheung, Tony, Anderson, Erica, Barton, Peter, Burgess, Jonathan, Byth, Kate, Cao, Qing, Castaldi, M. Paola, Chen, Huawei, Chiarparin, Elisabetta, Carbajo, Rodrigo J., Code, Erin, Cow

Journal:

ACS Chemical Biology

Year:

2018

Language:

english

File:

PDF, 6.05 MB

english, 2018

32

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

Tron, Adriana E., Belmonte, Matthew A., Adam, Ammar, Aquila, Brian M., Boise, Lawrence H., Chiarparin, Elisabetta, Cidado, Justin, Embrey, Kevin J., Gangl, Eric, Gibbons, Francis D., Gregory, Gareth P

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.48 MB

english, 2018

33

Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines

Linnane, Emily, Davey, Paul, Zhang, Pei, Puri, Sanyogitta, Edbrooke, Mark, Chiarparin, Elisabetta, Revenko, Alexey S, Macleod, A Robert, Norman, Jim C, Ross, Sarah J

Journal:

Nucleic Acids Research

Year:

2019

File:

PDF, 11.73 MB

2019

34

Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines

Linnane, Emily, Davey, Paul, Zhang, Pei, Puri, Sanyogitta, Edbrooke, Mark, Chiarparin, Elisabetta, Revenko, Alexey S, Macleod, A Robert, Norman, Jim C, Ross, Sarah J

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 11.73 MB

english, 2019

35

Observing an antisense drug complex in intact human cells by in-cell NMR

Schlagnitweit, Judith, Friebe Sandoz, Sarah, Jaworski, Aleksander, Guzzetti, Ileana, Aussenac, Fabien, Carbajo, Rodrigo J., Chiarparin, Elisabetta, Pell, Andrew J., Petzold, Katja

Journal:

Year:

2019

Language:

english

File:

PDF, 1.21 MB

english, 2019

36

Lipidated stapled peptides targeting the acyl binding protein UNC119

Chromm, Philipp, Adihou, Hélène, Kapoor, Shobhna, Vazquez-Chantada, Mercedes, Davey, Paul, Longmire, David, Hennes, Elisabeth, Hofer, Walter, Küchler, Philipp, Chiarparin, Elisabetta, Waldmann, Herber

Journal:

Year:

2019

Language:

english

File:

PDF, 1.82 MB

english, 2019

37

Cover Feature: Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119 (ChemBioChem 24/2019)

Cromm, Philipp M., Adihou, HÃ©lÃ¨ne, Kapoor, Shobhna, VazquezâChantada, Mercedes, Davey, Paul, Longmire, David, Hennes, Elisabeth, Hofer, Walter, KÃ¼chler, Philipp, Chiarparin, Elisabetta, Waldmann,

Journal:

Year:

2019

File:

PDF, 2.77 MB

2019

38

Discovery of AZD9833, a potent and orally bioavailable selective estrogen receptor degrader and antagonist.

Scott, James S., Moss, Thomas A., Balazs, Amber, Barlaam, Bernard, Breed, Jason, Carbajo, Rodrigo, Chiarparin, Elisabetta, Davey, Paul, Delpuech, Oona, Fawell, Stephen, Fisher, David, gagrica, sladjan

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.27 MB

2020

39

Lipophilicity trends upon fluorination of isopropyl, cyclopropyl and 3-oxetanyl groups

Jeffries, Benjamin, Wang, Zhong, Troup, Robert I, Goupille, AnaÃ¯s, Le Questel, Jean-Yves, Fallan, Charlene, Scott, James S, Chiarparin, Elisabetta, Graton, JÃ©rÃ´me, Linclau, Bruno

Journal:

Beilstein Journal of Organic Chemistry

Year:

2020

File:

PDF, 839 KB

2020